卵巢过度刺激综合征(OHSS)是辅助生殖技术的控制性超排卵过程中较常见也是最严重的并发症,其发病机理尚未完全阐明。近期研究表明,白细胞介素(IL)-1,-2,-6,-8,-10和肿瘤坏死因子(TNF)、血管内皮生长因子(VEGF)等与OHSS密切相关,在引起OHSS的高血管通透性中起重要作用。进一步探索这些细胞因子与OHSS的关系将为了解其发生发展机理提供理论基础,有利于OHSS的预测、预防和治疗 Ovarian hyperstimulation syndrome (OHSS) is the most common and serious complication of controlled ovulation in assisted reproductive technology. The pathogenesis of OHSS is not fully elucidated. Recent studies have shown that interleukin (IL) -1, -2, -6, -8, -10 and tumor necrosis factor (TNF), vascular endothelial growth factor (VEGF) are closely related to OHSS, causing high OHSS Vascular permeability plays an important role. Further exploration of the relationship between these cytokines and OHSS will provide a theoretical basis for understanding its mechanism of development and development, and be of benefit in the prediction, prevention and treatment of OHSS