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目的观察醒脑解郁胶囊治疗抑郁症的疗效。方法将我院治疗的82例抑郁症随机分为治疗组(醒脑解郁中药汤剂+黛力新+醒脑解郁胶囊)和对照组(黛力新),疗程8 W,治疗期间用汉密顿抑郁量表(HAMD)对患者治疗前后分别进行疗效评估。结果经汉密尔顿抑郁量表评分结果显示,治疗组在第1 W、第2 W末HAMD分值均明显低于对照组,而在第6 W末,两组患者的HAMA分值差异亦有统计学意义。治疗组显效率为72.5%,有效率为100%;对照组分别为47.5%8、2.5%,两组差异有统计学意义(P<0.05)。在不良反应方面,治疗组亦优于对照组(P<0.05)。结论醒脑解郁胶囊具有醒脑解郁、化痰活血的作用,其治疗抑郁症疗效、安全性、依从性均较好,值得临床推广。
Objective To observe the therapeutic effect of Xingnao Jieyu capsule on depression. Methods 82 cases of depression treated in our hospital were randomly divided into treatment group (Xingnao Jieyu Decoction + Deanxine + Xingnao Jieyu Capsule) and control group (Deanxit) with a course of treatment of 8 W during treatment The Hamilton Depression Rating Scale (HAMD) evaluated the efficacy of the treatment before and after treatment. Results The Hamilton Depression Scale score showed that the HAMD score of the treatment group was significantly lower than that of the control group at the first W and the second W, while at the end of the 6th WAM, the HAMA scores of the two groups were also statistically different significance. The effective rate was 72.5% and the effective rate was 100% in the treatment group and 47.5% 8 and 2.5% in the control group, respectively, with significant difference between the two groups (P <0.05). In adverse reactions, the treatment group also better than the control group (P <0.05). Conclusion Xingnao Jieyu Capsule has the functions of Xingnao Jieyu, phlegm and blood circulation, and its efficacy, safety and compliance in the treatment of depression are better and worthy of clinical promotion.