作者用较小剂量的β-ser干扰素(IFN)成功地治疗毛细胞白血病12例,其中男10例,女2例,平均年龄45岁。有10例曾分别经过脾切除(7例)、化疗(2例)及放疗(1例)。确诊至β-serIFN治疗的中位时间是8.5个月。治疗前3例患者脾大、1例肝大、8例周围血中找到毛细胞。β-serIFN90×10~6U/次,3次/周静注。治疗1年后,6例患者改皮下注 The authors successfully treated hairy cell leukemia in 12 patients with a lower dose of interferon-alpha (IFN), including 10 males and 2 females, with an average age of 45 years. Ten cases had been splenectomy (7 cases), chemotherapy (2 cases) and radiotherapy (1 case). The median time to diagnosis of beta-serIFN therapy was 8.5 months. 3 cases before treatment of splenomegaly, 1 case of liver, hair cells found in 8 cases of peripheral blood. β-serIFN90 × 10 ~ 6U / time, 3 times / week intravenous injection. After 1 year of treatment, 6 patients changed skin and bet