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用抗凝剂治疗肾脏病有20年左右,但至今对抗凝疗法的评价尚有争论,两派各抒己见,并有临床或实验工作为依据。然而,最后的结论恐怕还要通过读者们在自己的工作中作出正确的评价,为此将两派的代表性意见归纳介绍于后供读者们参考。 Kincaid-Smith很久以前就发现肾脏疾病发病机理中血凝和/或血小板栓子的重要作用,形态学表现揭示纤维蛋白原沉积和血小板栓塞是肾脏疾病进展的重要原因,因而提出了打断凝血环节或阻止血小板
There are about 20 years of treatment of kidney disease with anticoagulants, but so far the evaluation of anticoagulation therapy is still controversial, the two factions each express their opinions, and clinical or experimental work as the basis. However, I am afraid the final conclusion is still through the readers in their own work to make the right evaluation, for which the representative of the two factions were summarized for later reference for readers. Kincaid-Smith long ago discovered the important role of blood clotting and / or platelet emboli in the pathogenesis of renal disease. Morphological findings revealed that fibrinogen deposition and platelet embolism are important causes of kidney disease progression. Therefore, Or prevent platelets