人工合成抑制肽(商品名Sandostatin)具有与天然生长抑素(somatostatin)相似的作用,可加速胰外瘘的闭合。本文前瞻性评价其临床应用的安全性和有效性。本组5例胰外瘘病人(男4例,女1例,年龄29～61岁)中,高流量瘘2例,低流量瘘3例;1例(低流量)并发于胰腺类癌瘤切除术后,4例系慢性酒精性胰腺炎伴假性囊肿经皮引流后。治疗前,病人每日瘘排出量为30～750ml, Synthetic inhibitory peptide (Sandostatin) has a similar effect as somatostatin and can accelerate the closure of pancreatic fistula. This prospective evaluation of the clinical application of the safety and effectiveness. The group of 5 cases of pancreatic fistula patients (4 males and 1 females, aged 29 to 61 years), 2 cases of high-flow fistula, low-flow fistula in 3 cases; 1 case (low-flow) in pancreatic carcinoid resection After surgery, 4 cases of chronic alcoholic pancreatitis with pseudocyst after percutaneous drainage. Before treatment, the patient’s daily discharge of fistula 30 ~ 750ml,