海参是无脊椎动物,不具有特异性免疫,只具有非特异性免疫。免疫增强剂能增强机体免疫应答,增强海参对病毒、细菌、真菌和寄生虫等引起疾病的抵抗力,对疾病的防控起到积极的作用。随着科技的发展,对海参免疫机制及其免疫增强剂有了进一步的研究。本文针对近年来海参的免疫机制及免疫增强剂对其影响的研究进行了综述及展望。 Sea cucumber is an invertebrate, does not have specific immunity, only with non-specific immunity. Immune enhancers can enhance the body’s immune response, enhance sea cucumber on viruses, bacteria, fungi and parasites and other diseases caused by resistance, disease prevention and control play a positive role. With the development of science and technology, further research has been done on the immune mechanism of sea cucumber and its immune enhancers. In this paper, the immunological mechanism of sea cucumber in recent years and the impact of immune enhancers on the research were reviewed and prospects.