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我们分析了1978～1992年住院并门诊复查的134例IDDM病例,侧重其并发症与病程的关系。男性53例,女性81例,男:女=1:1.52。年龄0～5岁男10名.女14名;5岁男17名.女31名;10岁男76名、女36名。各年龄组均女多于男,最小2个月,10～14岁年龄组最多。家族史131例中17例阳性,占12.9％。入院前病程:33.5％病儿在半月内住院,55.2％在1月内住院,80％在半年内住院。并发症随病程增长而增加,但家长积极配合治疗、定期检查者并发症少。并发症中依次为:高血脂37例、肾功能减退32例,心肌损害23例,白内障9例,甲状腺肿与肝功能减退各8例,视网膜病变6例,高血压2例。神经性膀胱、肺结核与巨幼贫血各1例。高血脂多见于酮症酸中毒住院的新、老病儿及在门诊病情控制不好者,后者往往并有肝大且功能减低。曾有1例高血脂(甘油三酯高达1100mg％)引致昏迷者,其血糖与脑脊液均正常。多数高血脂在2～4周恢复。我们查
We analyzed 134 idiopathic IDDM cases admitted to our hospital from 1978 to 1992 and focused on the relationship between the complication and course of disease. 53 males and 81 females, male: female = 1: 1.52. Age 0 to 5 years old male 10. Female 14; 5-year-old male and female 17. 31-year-old male 76, female 36. Each age group more than men, the youngest 2 months, 10 to 14 age group most. Among 131 cases of family history, 17 cases were positive, accounting for 12.9%. Pre-admission course of disease: 33.5% of sick children were hospitalized within half a month, 55.2% were hospitalized in January and 80% were hospitalized within six months. Complications increased with the course of disease, but parents actively cooperate with the treatment, regular check fewer complications. The complications included 37 cases of hyperlipidemia, 32 cases of renal dysfunction, 23 cases of myocardial damage, 9 cases of cataract, 8 cases of goiter and liver dysfunction, 6 cases of retinopathy and 2 cases of hypertension. Neurogenic bladder, tuberculosis and megaloblastic anemia in 1 case. Hyperlipidemia more common in patients with ketosis acidosis hospitalized, old sick children and poor control of outpatient conditions, which often have large liver and reduced function. There was a case of hyperlipidemia (triglycerides up to 1100mg%) caused by coma, the blood sugar and cerebrospinal fluid were normal. Most hyperlipidemia in 2 to 4 weeks recovery. We check