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目的探讨定量组织速度成像技术在糖尿病患者左室舒张早期心肌松弛性功能中的应用。方法选取2013年4月—2014年4月南宁市第八人民医院收治的糖尿病合并左室肥厚患者32例设为试验组,选取同期体检的32例健康者为对照组。采用组织速度成像技术对患者左房室环与侧壁交界处测定左房室环舒张早期峰值运动速度和舒张晚期峰值运动速度等指标〔左前降支(LAD)、左心室舒张末期内径(LVEDD)、室间隔厚度(IVS)、左心室后壁厚度(LVPW)、左心室心肌质量指数(LVMI)、左室短轴缩短率(FS)、E、E/A、MEm、A、MAm、E/MEm〕,分析定量组织速度成像技术在糖尿病患者左室舒张早期心肌松弛性功能中的应用。结果试验组患者糖化血红蛋白、心率高于对照组,体质指数(BMI)低于对照组,差异有统计学意义(P<0.05)。试验组患者LAD、LVEDD、IVS、LVPW、LVMI、FS均高于对照组,差异有统计学意义(P<0.05);两组左心室射血分数(LVEF)比较,差异无统计学意义(P>0.05)。试验组患者E、E/A、MEm均低于对照组,差异有统计学意义(P<0.05);A、MAm、E/MEm、TDI~Tei高于对照组,差异有统计学意义(P<0.05)。结论定量组织速度成像技术通过检测患者左房室环运动速度能够准确的反应糖尿病患者左室舒张功能。
Objective To investigate the application of quantitative tissue velocity imaging in early left ventricular diastolic myocardial relaxation in patients with diabetes mellitus. Methods From April 2013 to April 2014, 32 patients with diabetes mellitus and left ventricular hypertrophy in Nanning Eighth People’s Hospital were enrolled as the experimental group, and 32 healthy subjects in the same period were selected as the control group. Tissue velocity imaging was used to measure left anterior descending artery (LAD), left ventricular end-diastolic dimension (LVEDD), left ventricular diastolic diameter (LVEDD) and left ventricular anterior descending peak velocity (IVS), left ventricular posterior wall thickness (LVPW), left ventricular mass index (LVMI), left ventricular fractional shortening (FS), E, E / A, MEm, A, MAm and E / MEm〕, analysis of quantitative tissue velocity imaging in patients with diastolic left ventricular diastolic early myocardial relaxation function. Results The HbA1c in the experimental group was higher than that in the control group, and the body mass index (BMI) was lower than that in the control group. The difference was statistically significant (P <0.05). The LAD, LVEDD, IVS, LVPW, LVMI and FS in the experimental group were significantly higher than those in the control group (P <0.05). There was no significant difference in the left ventricular ejection fraction (LVEF) between the two groups > 0.05). The levels of E, E / A and MEm in the experimental group were significantly lower than those in the control group (P <0.05), and the differences were statistically significant (P <0.05). Conclusion Quantitative tissue velocity imaging can accurately measure left ventricular diastolic function in diabetic patients by detecting the velocity of left ventricular ring.