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1 多囊卵巢综合征(PCOS)的发病机理新的观点认为胰岛素拮抗(insulin resistance) 与高胰岛素是 PCOS 常见的表现,胰岛素拮抗可能是原发的干扰因素伴有高雄激素基因而起作用。可能直接关系到胰岛素受体数目的减少,受体形成抗体或受体有缺陷。PCOS 患者无论肥胖与否,即使月经周期正常伴有高雄激素征 euglycemic glucose clamp tech-niques 均显示胰岛素拮抗。但是单从这些现象仍不能
1 pathogenesis of polycystic ovary syndrome (PCOS) The new view that the insulin resistance (insulin resistance) and hyperinsulinemia is a common manifestation of PCOS, insulin antagonism may be the primary interfering factor associated with hyperandrogenism gene and play a role. May be directly related to the reduction of the number of insulin receptors, receptor-forming antibodies or receptors defective. Regardless of obesity or whether PCOS patients, even if the menstrual cycle is normal accompanied by hyperandrogenism euglycemic glucose clamp tech-niques are shown in insulin antagonism. However, these phenomena alone still can not