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尿路感染(UTIs)发病率很高,但理想的治疗仍有争论。新抗菌药能有效地治疗UTIs,一些药物将代替具有肾毒性的氨基糖甙抗生素。UTIs治疗的成功与否,取决于药物的有效抗菌浓度及细菌对药物的敏感性,通常要求尿药浓度高于血者。理论上认为,应用杀菌剂更为可取,但尚无确切的证据说明杀菌剂优于抑菌剂。本文旨在讨论UTIs的治疗进展,包括妇女急性尿痛、肾盂肾炎、前列腺炎和无症状性菌尿。
The incidence of urinary tract infections (UTIs) is high, but the ideal treatment remains controversial. New antibacterials are effective in treating UTIs, and some drugs will replace aminoglycoside antibiotics with nephrotoxicity. The success of UTIs treatment, depending on the effective antibacterial concentration of drugs and the sensitivity of bacteria to drugs, usually require urine concentration is higher than blood. In theory, the use of fungicides is preferable, but there is no conclusive evidence that fungicides are superior to bacteriostats. This article aims to discuss the treatment of UTIs, including acute dysuria in women, pyelonephritis, prostatitis and asymptomatic bacteriuria.