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目的 :探讨巴曲抗栓酶治疗急性心肌梗死 (AMI)的临床疗效。方法 :30例 AMI患者在给予常规治疗的基础上 ,加用巴曲抗栓酶 ,分别于第 1、3、5天给予 1 0 u、5u、5u,以生理盐水 1 0 0 ml稀释后静脉滴注 1 h,与对照组比较 ,观察疗效及实验室指标。结果 :治疗 1周后 ,治疗组与对照组相比 ,左室射血分数增加 ,QT离散度减小 ,AMI后心绞痛发生率下降 ,纤维蛋白原明显降低 ,均有显著性差异。结论 :巴曲抗栓酶治疗 AMI具有改善左室功能 ,减少室性心律失常发生等作用 ,对发病延迟来院患者疗效好 ,使用方便、安全 ,值得推广。
Objective: To investigate the clinical efficacy of batroxobin in the treatment of acute myocardial infarction (AMI). Methods: Thirty patients with AMI were given routine therapy, plus batroxobin on day 1, day 3, day 5, day 5, day 5 after intravenous injection of diluted 100 ml normal saline Instillation 1 h, compared with the control group, observe the efficacy and laboratory indicators. Results: Compared with the control group, the left ventricular ejection fraction increased, the QT dispersion decreased, the incidence of angina pectoris decreased and the fibrinogen decreased obviously after treatment for one week in the treatment group. Conclusion: The antithrombotic therapy with batroxobin can improve left ventricular function and reduce the occurrence of ventricular arrhythmia. It is effective and easy to use and safe for patients with delayed onset and is worth promoting.