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克氏综合征睾丸病变伴随染色体异常已有文献报道,目前还不知道克氏综合征染色体异常是否引起免疫学反应。本研究在10例克氏综合征患者中作了对精子抗原的体液和细胞免疫检测. 10例克氏综合征患者年龄20～35岁表现为无精子、小睾丸和男子乳房发育,性染色体阳性,较高百分率Barr小体(8.23％),睾丸活检显示典型的曲细精管透明性变和间质细胞增生,确定诊断为克氏
Kirschner’s disease testicular lesions associated with chromosomal abnormalities have been reported in the literature, it is still unknown whether Klinefelter syndrome chromosomal abnormalities caused by immunological reactions. In this study, 10 cases of patients with Klinefelter syndrome were tested for sperm antigen in humoral and cellular immunity.All 10 cases of Keshi syndrome patients aged 20 to 35 years showed azoospermia, testis and men with breast development, sex chromosome positive , A high percentage of Barr bodies (8.23%), testicular biopsies showing typical changes in the seminiferous tubules transparency and interstitial cell hyperplasia, to determine the diagnosis of Kirschner