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群多普利是一个不含流基的ACE抑制剂，口服后迅速水解为活性产物群多普利拉（trandolaPrilat），后者经尿（1／3）和粪（2／3）排泄。健康人服药后，累积有效半减期24小时。在血浆和组织水平产生明显而持久的ACE抑制效应。1剂量原发性高血压每日口服本品2mg共2周，可使血压下降
Trandolapiride is a flow-based ACE inhibitor that is rapidly hydrolyzed orally to the active product trandolaPrilat, which is excreted by urine (1/3) and excrement (2/3). Healthy people take the medicine, cumulative effective half-period of 24 hours. Significant and long lasting ACE inhibitory effects at plasma and tissue levels. 1 dose of essential hypertension daily oral administration of 2mg for 2 weeks, can make blood pressure decreased