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小儿急性胰腺炎的实验室诊断标志物包括淀粉酶及同工酶、脂肪酶、C反应蛋白、尿胰蛋白酶原2、胰蛋白酶原激活肽、降钙素原等。淀粉酶检测方法简便、经济,但敏感性和特异性不够理想,在进行淀粉酶检测基础上通过脂肪酶检测可提高诊断率。尿胰蛋白酶原2检测可减少漏诊。胰蛋白酶原激活肽、C反应蛋白和降钙素原检测可判断病情,尤其降钙素原不仅能早期反映病情轻重,而且可以监测病情发展。
Laboratory diagnostic markers for acute pancreatitis in children include amylase and isozyme, lipase, C-reactive protein, urinary trypsinogen 2, trypsinogen, procalcitonin and the like. Amylase detection method is simple, economical, but the sensitivity and specificity are not ideal, based on the amylase detection by lipase detection can improve the diagnostic rate. Urinary trypsinogen 2 test can reduce missed diagnosis. Trypsinogen activation peptide, C-reactive protein and procalcitonin detection can determine the condition, especially procalcitonin not only reflect the severity of the disease early, but also to monitor the progression of the disease.