用山莨菪碱溶液和一些其他药物涂以局部皮肤浅表血管，测量血管宽度，观察其效应。结果显示２％山莨菪碱扩张局部皮肤浅表血管的显效率达８０％，与其他药物比较有显著性差异，Ｐ＜０．０１，临床应用５０例（静脉输液有困难，血管条件不良者），一次性穿刺成功３８例，重复涂药后穿刺成功８例，未充盈扩张４例。所用患者均无局部或全身不良反应，我们认为，局部应用２％山莨菪碱可扩张局部浅表血管，该方法有一定的实用价值。 Topical skin superficial blood vessels were coated with anisodamine solution and some other drugs to measure the vascular width and observe its effect. The results showed that the apparent rate of 2% anisodamine expansion superficial blood vessels in the skin was 80%, compared with other drugs were significantly different, P <0.01, clinical application of 50 cases (intravenous infusion difficulties, poor vascular conditions) 38 cases were successfully punctured at a time, 8 cases were successfully punctured after repeated application, and 4 cases were not fully expanded. All patients used have no local or systemic adverse reactions, we believe that topical application of 2% anisodamine can expand local superficial blood vessels, the method has some practical value.