目的 :了解大鼠内淋巴囊的细胞增殖状态。方法 :选用 10只健康成年 S-D大鼠 ,腹腔注射 5 -溴 -2′-脱氧尿嘧啶核苷 ( Brd Urd)后 ,取颞骨作组织学处理 ,用抗 Brd Urd单克隆抗体 ,通过免疫组织化学技术 ,观察内淋巴囊 S期细胞的定位与分布。结果 :在内淋巴囊上皮、上皮下区域和囊腔内存在着散在的 Brd Urd+ 细胞 ,它们多位于内淋巴囊的中间部 ;耳蜗未发现阳性细胞。结论 :大鼠内淋巴囊具有细胞增殖功能 ,可能是内耳具有细胞更新功能的重要部位 Objective: To understand the cell proliferation status of endolymphatic sac in rats. Methods: Ten healthy adult SD rats were injected intraperitoneally with 5 - bromo - 2’- deoxyuridine (Brd Urd). The temporal bone was taken for histological treatment. Anti - Brd Urd1 monoclonal antibody Technique to observe the location and distribution of S phase cells in endolymphatic sac. Results: There were scattered Brd Urd + cells in the endolymphatic sac, subepithelial region and cyst. Most of them were located in the middle part of the lymphatic sac. No positive cells were found in the cochlea. Conclusion: The endolymphatic sac in rats has the function of cell proliferation, which may be an important part of the inner ear with cell renewal function