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目的探讨冠心病急性心肌梗死伴高危快速型心律失常患者采用胺碘酮治疗的临床效果。方法 70例冠心病急性心肌梗死伴高危快速型心律失常患者作为研究对象,随机分为对照组和观察组,每组35例,对照组采用普鲁卡因胺治疗,观察组采用胺碘酮进行治疗,比较两组治疗效果。结果观察组治疗总有效率为94.29%,明显高于对照组的74.29%,差异具有统计学意义(χ~2=5.285,P=0.022<0.05)。观察组不良反应发生率为8.57%,明显低于对照组的28.57%,差异具有统计学意义(χ~2=4.629,P=0.031<0.05)。结论冠心病急性心肌梗死伴高危快速型心律失常患者采用胺碘酮治疗效果显著,具有较高安全性,可推广应用。
Objective To investigate the clinical effect of amiodarone in patients with coronary heart disease with acute myocardial infarction and high-risk tachyarrhythmia. Methods Seventy patients with coronary heart disease with acute myocardial infarction and high-risk tachyarrhythmia were randomly divided into control group and observation group with 35 cases in each group. The control group was treated with procainamide and the observation group was treated with amiodarone Treatment, the treatment effect of two groups were compared. Results The total effective rate of the observation group was 94.29%, which was significantly higher than that of the control group (74.29%). The difference was statistically significant (χ ~ 2 = 5.285, P = 0.022 <0.05). The incidence of adverse reactions in the observation group was 8.57%, which was significantly lower than that in the control group (28.57%). The difference was statistically significant (χ ~ 2 = 4.629, P = 0.031 <0.05). Conclusion Amiodarone in patients with coronary heart disease with acute myocardial infarction and high-risk tachyarrhythmia has a significant effect, which is safe and can be widely applied.