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目的为获得北京甲 3流感暴发中其它主要呼吸道病毒介入和血清学依据。方法应用系列呼吸道病毒桥联酶标试剂盒对 2 0 4例患者分泌物进行多病毒抗原检测 ;应用间接免疫荧光法对流行前人群 5 0例和流行后患者恢复期血清 41例 ,分别作呼吸道合胞病毒 (RSV) ;副流感病毒 3型 (PIV3)以及腺病毒 7型 (Adv7)的血清学检测。结果 2 0 4例标本中病毒总检出率为6 7.1% (137/2 0 4) ,其中甲型流感 (Flu A)总检出率为 5 7.3% (117/2 0 4) ,Flu A两种病毒以上混合感染率为 70 .9% (83/117) ,以RSV与 Flu A混合感染最高为 43.6 % ;Flu B和 PIV与 Flu A次之 ;Adv再次之。流行前后 RSV、PIV3和 Adv7血清比较 ,抗体均大幅度提高。结论北京 1998年 12月是以甲 3流感为主并存在其它病毒 RSV、PIV3和 Adv7的介入和混合协同感染。
Aims To obtain the interventional and serological evidence of other major respiratory viruses in the outbreak of Influenza A 3 in Beijing. Methods A series of respiratory viral cross-linked enzyme-linked enzyme kit was used to detect polytope antigens in 240 patients with secretions. Fifty cases of pre-epidemic population and 41 cases of post-epidemic post-epidemic phase serum were detected by indirect immunofluorescence. (RSV); serological detection of parainfluenza virus type 3 (PIV3) and adenovirus type 7 (Adv7). Results The total detection rate of the virus in 204 samples was 6 7.1% (137/2 0 4). The total detection rate of Flu A was 5 7.3% (117/2 0 4). Flu A The combined infection rates of the two viruses were 70.9% (83/117), with a maximum of 43.6% with RSV mixed with Flu A; Flu B and PIV followed by Flu A; and Adv again. Before and after the epidemic RSV, PIV3 and Adv7 serum, the antibodies were significantly increased. Conclusion Beijing December 1998 was predominantly Influenza A 3 with intervening and mixed co-infections of other viruses RSV, PIV3 and Adv7.