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目的评价选择性颈清扫对T1,2N0M0舌癌患者预后的影响。材料与方法检索国内外已公开发表的关于选择性颈清扫对T1,2N0M0舌癌患者预后影响的对照研究,应用Meta分析进行统计学处理。结果(1)选择性颈清扫对术后复发的影响:符合标准的文献7篇,总样本数742,其中选择性颈清扫组291人,观察组451人。Meta分析结果:选择性颈清扫组相对于观察组的复发优势比OR=0.41,95%可信区间(0.22,0.75),具有统计学意义。(2)选择性颈清扫对术后生存的影响:符合标准的文献5篇,总样本数614,其中选择性颈清扫组222人,观察组392人。Meta分析结果:选择性颈清扫组相对于观察组的生存优势比OR=1.61,95%可信区间(1.14,2.27),具有统计学意义。结论选择性颈清扫可减少T1,2N0M0舌癌患者术后的复发并能延长生存期。
Objective To evaluate the effect of selective neck dissection on the prognosis of T1 and 2N0M0 tongue cancer patients. Materials and Methods A controlled study of the effect of selective neck dissection on the prognosis of T1 and 2N0M0 tongue cancer patients has been published at home and abroad. Meta-analysis was used for statistical analysis. Results (1) The effect of selective neck dissection on postoperative recurrence: There are 7 literatures whose total number is 742, including 291 cases of selective neck dissection and 451 cases of observation group. The results of Meta-analysis showed that OR = 0.41, 95% confidence interval (0.22, 0.75) in the selective neck dissection group compared with the observation group were statistically significant. (2) The effect of selective neck dissection on postoperative survival: There are 5 literatures with the total number of 614, including 222 selective neck dissection group and 392 observation group. The results of Meta-analysis: The survival odds ratio (OR = 1.61, 95% confidence interval, 1.14, 2.27) in the selective neck dissection group compared with the observation group was statistically significant. Conclusion The selective neck dissection can reduce the recurrence of T1,2N0M0 tongue cancer patients and prolong the survival time.