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目的 :比较观察纯溶栓酶与低分子右旋糖酐 +复方丹参治疗脑梗死的临床及血液流变学变化。方法 :经 CT或MRI确诊的 147例脑梗死并有高纤维蛋白原血症患者分成治疗组和对照组 ,治疗组 91例用纯溶栓酶 15～ 2 5 BU(总量 )静脉滴注 ;治疗前、后评定患者的神经功能缺损 ,并检测血液流变学指标。结果 :治疗组的临床症状及血液流变学较对照组明显改善。治疗组总显效 (基本痊愈 +显著进步 ) 75例 (82 .4% )。结论 :纯溶栓酶治疗脑梗死效果确切 ,疗程短 ,且无明显不良反应。
Objective: To observe the clinical and hemorheological changes of cerebral infarction treated with pure thrombolytic enzyme and dextran plus salvia miltiorrhiza. Methods: One hundred and seventy-seven patients with cerebral infarction and hyperfibrinogenemia diagnosed by CT or MRI were divided into treatment group and control group. In the treatment group, 91 patients were treated with pure thrombolytic enzyme (15-2.5 BU) Before and after treatment, patients were assessed for neurological deficits and hemorheological parameters were measured. Results: The clinical symptoms and hemorheology in the treatment group were significantly improved compared with the control group. The treatment group was markedly effective (basic recovery + significant improvement) in 75 cases (82.4%). Conclusion: The pure thrombolytic enzyme treatment of cerebral infarction exact effect, short course of treatment, and no significant adverse reactions.