溴隐停系一种半合成的麦角生物碱溴化物。其阻滞催乳素的作用是由于它一方面直接抑制了垂体前叶催乳素分泌细胞,使催乳素分泌量减少。但对其它性腺激素无影响(仅肢端肥大症患者血循环中生长激素减少);另一方面是通过多巴胺原间接作用于视丘下部,使催乳素的产生受抑制和促甲状腺素的释放,但很少或无麦角生物碱的其它作用(如收缩子宫)。高催乳素血症产生的闭经、性功能障碍的原因可能是高催乳素直接作用于卵巢受体,阻滞了卵巢受体对促性腺激素的反应能力,抑或由于高催乳素抑制了卵巢黄体功能,使孕期的生成和分泌减少。许多作者研究指出,无论男女性,当催乳素水平增高时,则影响了促性腺激素对性腺的 Bromocriptine is a semisynthetic ergot alkaloid bromide. Its role in blocking prolactin is due to its direct inhibition of the anterior pituitary prolactin secretion cells on the one hand, so that prolactin secretion decreased. But no effect on other sex hormones (acromegaly patients only reduced blood circulating growth hormone); the other hand through the indirect effect of dopamine on the hypothalamus, so that the production of prolactin and thyroid stimulating hormone release, but on the other hand, Little or no other role of ergot alkaloids (such as contraction of the uterus). The causes of amenorrhea and sexual dysfunction caused by hyperprolactinemia may be that the high prolactin directly acts on the ovarian receptor, blocks the ovarian receptor’s ability to respond to gonadotrophin, or inhibits ovarian corpus luteum function due to high prolactin , So that the generation and secretion during pregnancy to reduce. Many authors indicate that both men and women, when elevated levels of prolactin, affect the effect of gonadotropins on gonadal