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利用FTIR光谱法和计算机辅助解析(去卷积、曲线拟合)研究了环磷腺苷(cAMP)对膜蛋白二级结构的影响。发现不同浓度的cAMP对膜蛋白二级结构具有不同的影响,即cAMP的浓度变化对膜蛋白构象具有调控作用。
The effects of cAMP on membrane protein secondary structure were investigated by FTIR spectroscopy and computer-assisted analysis (deconvolution, curve fitting). It was found that different concentrations of cAMP have different effects on the secondary structure of membrane proteins, that is, the concentration of cAMP has a regulatory effect on membrane protein conformation.