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目的探讨45岁以下子宫内膜癌诊断与治疗。方法回顾分析2005年1月至2010年12月≤45岁子宫内膜癌19例病例资料,与同期>45岁的患者126临床资料作对比。结果本组19例占同期收治子宫内膜癌的13.1%(19/145),其中6例未孕,占31.5%,临床表现为阴道流血、排液、月经量多经期延长;18例诊刮确诊,1例外院因功血行子宫切除诊为内膜癌,需作补充手术住院;结论 18例手术治疗,1例孕激素治疗后促排卵妊娠,现已足月分娩。结论 45岁以下年轻妇女子宫内膜癌临床期别较早,病理类型主要为子宫内膜样腺癌,细胞分化、肌层侵润,差异无统计学意义。治疗以手术为主,对高危患者辅以放、化疗,对于有生育要求低危患者,可保留其生育功能。
Objective To investigate the diagnosis and treatment of endometrial cancer under 45 years old. Methods The data of 19 cases of endometrial carcinoma ≤ 45 years from January 2005 to December 2010 were retrospectively analyzed, which were compared with the clinical data of 126 cases of patients aged> 45 years old during the same period. Results The group of 19 cases accounted for 13.1% (19/145) of endometrial cancer in the same period, of which 6 were non-pregnant, accounting for 31.5%, the clinical manifestations of vaginal bleeding, drainage, menorrhagia prolonged; 18 cases of curettage One patient was diagnosed as endometrial cancer by hysteroscopic resection of hemodialysis due to endometriosis, and hospitalized for additional surgery. Conclusion 18 cases of surgical treatment and 1 case of ovulation induction after progestin therapy are now delivered in full term. Conclusion The young women younger than 45 years of age endometrial cancer earlier, the pathological type of endometrial adenocarcinoma, cell differentiation, myometrial invasion, the difference was not statistically significant. Surgical treatment of the main high-risk patients supplemented by radiotherapy and chemotherapy, low-risk patients with reproductive requirements, can retain their reproductive function.