人类间α胰蛋白酶ITI是一种血浆蛋白酶抑制剂,包含一条轻链bikunin和5条同源的重链,与另一种葡萄糖胺聚糖蛋白-透明质酸(HA)形成复合物,在肿瘤、炎症和免疫中起重要作用。本文就ITI基因在肿瘤中的研究进展作一综述。 Human Inter-alpha Tryptase ITI is a plasma protease inhibitor consisting of a light chain bikunin and five homologous heavy chains that form a complex with another glucosaminoglycan-hyaluronic acid (HA) , Inflammation and immunity play an important role. This article reviews the progress of ITI gene in cancer research.