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在建立人外周血液淋巴细胞β受体放射配基结合分析法的基础上,观察了35名老年人外周血淋巴细胞β受体系统的变化。发现老年人的β受体B_(max)值明显低于青年人,其淋巴细胞对异丙肾上腺素刺激的反应性及腺苷酸环化酶活力均告降低。
Based on the establishment of β-adrenoceptor binding assay for human peripheral blood lymphocytes, the changes of β receptor system in peripheral blood lymphocytes of 35 elderly were observed. Found that β-receptor B max in elderly people was significantly lower than that in young people. The lymphocyte response to isoproterenol stimulation and adenylyl cyclase activity were all reduced.