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目的对比研究静脉推注胺碘酮与普罗帕酮转复阵发性心房颤动的效果。方法122例房颤持续时间<48h的患者随机分为两组,胺碘酮组62例:胺碘酮5mg/kg10min内静脉推注;普罗帕酮组60例:普罗帕酮70mg静脉推注,5～10min注完。观察30min若未转复可重复应用。结果转复率:胺碘酮组69·4%(43/62),普罗帕酮组60%(36/60),两组转复率比较差异无统计学意义(P>0·05)。结论胺碘酮和普罗帕酮对阵发性房颤均有较高的转复率。
Objective To compare the effects of intravenous amiodarone and propafenone on paroxysmal atrial fibrillation. Methods A total of 122 patients with atrial fibrillation lasting less than 48 hours were randomly divided into two groups: 62 in amiodarone group: intravenous injection of amiodarone 5 mg / kg in 10 min; 60 in propafenone group: 70 mg in propafenone group, 5 ~ 10min note finished. Observed 30min if not transferred can be repeatedly applied. Results The recovery rate was 69.4% (43/62) in amiodarone group and 60% (36/60) in propafenone group. There was no significant difference in the recovery rate between the two groups (P> 0.05). Conclusions Amiodarone and propafenone have higher conversion rate to paroxysmal atrial fibrillation.