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目的探讨2型糖尿病患者合并高血压的危险因素。方法选取2012年5月—2015年5月南京市建邺医院内科收治的2型糖尿病患者80例,根据是否合并高血压将患者分为研究组和对照组,各40例。收集两组患者的性别、年龄、糖尿病病程等基本信息,并测量其身高、体质量、收缩压(SBP)、舒张压(DBP)等,计算体质指数(BMI)。同时测定空腹血糖(FPG)、糖化血红蛋白(Hb A1c)、总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、脂蛋白a〔LP(a)〕。2型糖尿病患者合并高血压的危险因素分析采用单因素和多因素Logistic回归分析。结果年龄、病程、身高、体质量、BMI、SBP、DBP是2型糖尿病患者合并高血压的影响因素(P<0.05)。FPG、Hb A1c、TC、TG、LDL-C、HDL-C、LP(a)是2型糖尿病患者合并高血压的危险因素(P<0.05)。结论 2型糖尿病患者合并高血压的危险因素包括年龄、糖尿病病程、身高、体质量、BMI、SBP、DBP、FPG、Hb A1c、TC、TG、LDL-C、HDL-C、LP(a)等。
Objective To explore the risk factors of hypertension in type 2 diabetic patients. Methods From May 2012 to May 2015, 80 patients with type 2 diabetes treated in Jianli Hospital of Nanjing were enrolled. Patients were divided into study group (40 cases) and control group (40 cases) according to whether they had hypertension or not. The basic information such as gender, age and duration of diabetes were collected and the height, body mass, systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured to calculate body mass index (BMI). Fasting plasma glucose (FPG), HbA1c, TC, TG, LDL-C, HDL-C, Lipoprotein a [LP (a)]. Risk factors for type 2 diabetes mellitus with hypertension were analyzed using single factor and multivariate logistic regression analysis. Results Age, duration, height, body weight, BMI, SBP and DBP were the influencing factors of hypertension in type 2 diabetic patients (P <0.05). FPG, Hb A1c, TC, TG, LDL-C, HDL-C and LP (a) were the risk factors for hypertension in type 2 diabetic patients (P <0.05). Conclusion The risk factors of hypertension in type 2 diabetic patients include age, duration of diabetes, height, body mass, BMI, SBP, DBP, FPG, Hb A1c, TC, TG, LDL-C, HDL-C, LP .