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目的:分析良恶性骨肿瘤的彩色多普勒超声血流动力学和声像图特征。方法:抽取2017年2月至2020年9月郑州大学附属肿瘤医院收治的骨肿瘤患者110例，均行彩色多普勒超声诊断。以病理诊断结果为“金标准”，分析彩色多普勒超声对骨肿瘤的诊断效能；比较良、恶性骨肿瘤的血流分级、血流动力学参数、声像图特征。结果:病理结果证实恶性43例，良性67例；采用彩色多普勒超声诊断出恶性46例，良性64例。彩色多普勒超声诊断鉴别骨肿瘤性质灵敏度为93.02%(40/43)、特异度为97.01%(65/67)、准确度为95.45%(105/110)、漏诊率为6.98%(3/43)、误诊率为8.96%(6/67)。恶性骨肿瘤血流分级优于良性者(n P<0.05)。与良性骨肿瘤相比，恶性骨肿瘤阻力指数、搏动指数较低，收缩期峰值流速、舒张末期流速、最大血流速度、最小血流速度较高(n P<0.05)。恶性骨肿瘤多表现为周围软组织浸润(83.72%，36/43)和骨皮质有破坏不连续(95.35%，41/43)，良性骨肿瘤声像图特征主要为无周围软组织浸润(82.09%，55/67)、骨皮质无破坏连续(88.06%，59/67)，比较差异有统计学意义(n P<0.05)。n 结论:彩色多普勒超声诊断鉴别骨肿瘤良恶性效果好，且良恶性骨肿瘤血流动力学和声像图特征存在显著差异，可为临床诊断鉴别提供丰富信息支持。“,”Objective:To analyze the hemodynamic and ultrasonic characteristics of color Doppler ultrasonograph in benign and malignant bone tumors.Methods:A total of 110 patients with bone tumors treated in Tumor Hospital Affiliated to Zhengzhou University from February 2017 to September 2020 were selected, and all of them underwent color Doppler ultrasonograph. Taking the pathological diagnosis results as the gold standard, the diagnostic value of color Doppler ultrasonograph for bone tumor was analyzed. The blood flow grading, hemodynamic parameters and ultrasonic characteristics of benign and malignant bone tumors were analyzed.Results:Pathological diagnosis confirmed 43 malignant cases and 67 benign cases. And color Doppler ultrasound confirmed 46 malignant cases and 64 benign cases. The sensitivity, specificity, accuracy, missed diagnosis rate, and misdiagnosis rate of color Doppler ultrasonograph were 93.02% (40/43), 97.01% (65/67), 95.45% (105/110), 6.98% (3/43) and 8.96% (6/67), respectively. The blood flow grading of malignant bone tumors was better than that of benign tumors (n P<0.05). Compared with benign bone tumors, malignant bone tumors had lower resistant index and pulsatility index, but had higher peak systolic velocity, end diastolic velocity, maximum velocity, and minimize velocity (n P<0.05). Malignant bone tumors were mainly characterized by infiltration of peripheral soft tissue (83.72%, 36/43) and discontinuous destruction of bone cortex (95.35%, 41/43), while benign bone tumors were characterized by no infiltration of peripheral soft tissue (82.09%, 55/67) and no continuous destruction of bone cortex (88.06%, 59/67), the differences between benign and malignant bone tumors was significant(n P<0.05).n Conclusions:Color Doppler ultrasound has a good value in differential diagnosis of benign and malignant bone tumors, and there are significant differences in hemodynamic and ultrasonic characteristics between benign and malignant bone tumors . It can provide rich information support for clinical differential diagnosis.