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目的探讨中晚期宫颈癌后装腔内放疗剂量分布的主要影响因素。方法取自2004年8月至2005年11月在我院接受根治性放疗的宫颈癌Ⅱ～Ⅲb期95例患者资料,后装腔内放疗定位应用自行设计制作的“后装定位-治疗多用平移床”,剂量分布偏移参数的确定依据A-B参考系统原则,偏移剂量以标准人体体模实测确定。结果病理类型、宫旁浸润、操作技巧等对剂量分布偏移有显著影响,临床分期无显著影响；剂量分布的偏移程度不能随着后装治疗的次数增加而减轻。结论后装腔内放疗实施定位是必要的,不仅可以明确实时后装腔内放疗等剂量曲线的位置、偏移的类型,也为盆腔适形放疗调整剂量分布、进一步修正放疗方案提供了医学依据。
Objective To investigate the main influencing factors of dose distribution of posterior cervical intraluminal radiotherapy in advanced cervical cancer. Methods From August 2004 to November 2005 in our hospital for radical radiotherapy of cervical cancer Ⅱ ~ Ⅲb 95 cases of patients with information, after the installation of intracavitary radiotherapy positioning their own design and manufacture of “after the positioning - treatment of multi-purpose translation Bed ”, the dose distribution offset parameters are determined according to the AB reference system principle, and the offset dose is measured by a standard human phantom. Results The type of pathology, uterine infiltration and operation skills had a significant effect on the dose distribution deviation, but no significant effect on the clinical stage. The deviation of the dose distribution could not be reduced with the increase of the number of post-treatment. Conclusion Posterior intraluminal radiotherapy positioning is necessary. It can not only clear the location of the dose curve and the type of offset, but also adjust the dose distribution for pelvic conformal radiotherapy and provide a medical basis for further radiotherapy regimen .