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目的探讨青年和老年组中晚期胃癌的临床内镜特点及病理特征。方法 对我院2000年1月～2009年12月经手术治疗并经病理证实的320例中晚期胃癌(包括45例青年人胃癌和275例老年人胃癌)资料进行回顾性分析。结果 胃癌部位比较,青年组以胃窦部居多,老年组贲门部比例增高;青年胃癌以弥漫型多见,病理分型多为差低分化型,恶性程度高。青年组Ⅲb、Ⅳ期比例、肝转移、腹膜转移率均高于老年组,两组比较差异有显著性。结论 中晚期青年胃癌以高度恶性弥漫型为主,发病呈上升趋势。青年胃癌恶性程度高,预后差,应加强对青年胃癌的认识及警惕。
Objective To investigate the clinical endoscopic features and pathological features of advanced gastric cancer in young and old patients. Methods The data of 320 cases of advanced gastric cancer (including 45 cases of young gastric cancer and 275 cases of elderly gastric cancer) surgically treated and pathologically confirmed in our hospital from January 2000 to December 2009 were analyzed retrospectively. Results Compared with the gastric cancer, the youth group had the most gastric antrum, and the proportion of cardia in the elderly group increased. The diffuse type of gastric cancer was more common in young patients, and the poorly differentiated type was the most common in gastric cancer. The proportion of stage Ⅲb, Ⅳ, liver metastasis and peritoneal metastasis in youth group were higher than those in the elderly group, the difference was significant between the two groups. Conclusions The middle and late stage young gastric cancer is characterized by highly malignant diffuse type, and the incidence is on the rise. Youthful gastric cancer has a high degree of malignancy and a poor prognosis. It is necessary to strengthen awareness and vigilance of young people with gastric cancer.