阿德福韦酯为抗乙型肝炎病毒药物核苷(酸)类似物中的一种,其主要不良反应为肾毒性,有致血清肌酸激酶(CK)升高、血清低磷性骨软化症的报道[1-4],也存在阿德福韦酯致Fanconi综合征的个案[5]。然而,并非上述表现均为阿德福韦酯所致。我们收治的1例乙型肝炎肝硬化患者,服用阿德福韦酯抗病毒治疗近4个月出现明显的肌无力、肌痛等表 Adefovir dipivoxil is one of the nucleoside (acid) analogs of anti-hepatitis B virus drugs. The main adverse reactions are nephrotoxicity, elevated serum creatine kinase (CK) and serum hypophosphatemic osteomalacia Reported [1-4], there Adefovir dipivoxil-induced Fanconi syndrome cases [5]. However, none of the above manifestations were due to adefovir dipivoxil. We admitted to a case of hepatitis B cirrhosis patients, taking adefovir dipivoxil treatment for nearly 4 months showed obvious muscle weakness, myalgia Table