多种肝脏疾病均可出现糖代谢异常［１，２］，表现为糖耐量减低、高胰岛素血症。文献报道较多的是各种急慢性肝炎和肝硬化，对原发性肝癌（以下简称肝癌）致糖代谢紊乱报道较少。本文旨在探讨肝癌糖代谢异常的特点，外周血胰岛素和Ｃ肽的变化及胰β细胞功能状态。１材料与方法 A variety of liver diseases can occur abnormal glucose metabolism [1,2], manifested as impaired glucose tolerance, hyperinsulinemia. Reported in the literature is a variety of acute and chronic hepatitis and cirrhosis of the liver, the primary liver cancer (hereinafter referred to as liver cancer) caused less sugar metabolism disorder. This article aims to investigate the characteristics of liver cancer abnormal glucose metabolism, changes in peripheral blood insulin and C-peptide and pancreatic β-cell function status. 1 materials and methods