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为了探索狂犬病的免疫预防方法,我们在嘉祥县对2185例被犬咬伤者,采用注射抗狂犬病血清联合狂犬病疫苗的方法,与单纯注射狂犬病疫苗的方法,进行了对比分析.自1991年1月到1994年12月被犬咬伤到该防疫站就诊者共2185人.按受伤时间依次编号填卡,按单双号随机分为A、B两组.将所有咬人犬隔离观察30d左右,凡有躁动、狂叫、流涎、瘫痪、呼吸衰竭死亡者,认定为狂犬.确定狂犬咬伤者,A组有28例,B组有100例.所有患者就诊后,立即处理伤口,先用双氧水冲洗.再用碘酒消毒,不包扎,不缝合,充分暴露.常规注射青链霉素3～7d.A组,按常规方法单独注射人用狂犬病疫苗;B组,在咬伤24h内注射抗狂犬病血清.应用方法,先做过敏试验.过敏者脱敏后再用.抗狂犬病血清总用量按80IU/kg计算,将总量的1/2剂量
In order to explore the rabies immunization prevention methods, we conducted a comparative analysis of 2185 cases of dog bites in rabies in Jiaxiang County by injecting anti-rabies serum combined with rabies vaccine and rabies vaccine alone. To the dog was bite in December 1994 to the epidemic prevention station a total of 2185. According to the time of injury card number, according to single and double numbers were randomly divided into A and B groups.All bite dogs were isolated and observed about 30d, All rabbits with restlessness, madness, salivation, paralysis and respiratory failure were identified as rabies.All rabbits with rabies bite were identified as having 28 cases in group A and 100 cases in group B. All patients were treated immediately after the wounds were treated with hydrogen peroxide Rinse and then disinfected with iodine, not bandaged, not sutured, fully exposed routine injection of streptomycin 3 ~ 7d.A group, according to the conventional method of human rabies vaccine alone injection; B group, bite within 24h injection Rabies serum application method, first do allergy test .And then use desensitization. Anti-rabies serum total dosage by 80IU / kg calculation, the total amount of 1/2 dose