5-羟色胺(5-hydrotytryptamine,5-HT)最早是从血清中发现的,故又称作血清素;又因其具有强烈的血管收缩作用,故又称为血清紧张素。它广泛分布于全身,是具有重要生理功能的生化物质。如因某些原因使体内的5-HT水平升高,则可能引起一系列异常反应。20世纪60年代以来,由于可导致血清5-HT水平的药物逐年增多,用药者的异常反应也随之多见,5-羟色胺综合征(serotonin syndrome,SS)的命名也就应运而生。 5-hydroxytryptamine (5-hydrotytryptamine, 5-HT) was first discovered from the serum, it is also known as serotonin; because of its strong vasoconstriction, it is also known as serum angiotensin. It is widely distributed throughout the body and is a biochemical substance with important physiological functions. If for some reason to raise the level of 5-HT in the body, it may cause a series of abnormal reactions. Since the 1960s, as the number of drugs that cause 5-HT levels in serum has been increasing year by year, the abnormal reaction of the drug users has become more common. The name of serotonin syndrome (SS) has come into being as well.