采用非接触型角膜内皮显微镜对大植片角膜穿透移植术后60例61眼移植片内皮进行了半年至10年的观察。其中55眼保持植片透明,其细胞密度为720-1680个/mm~2,显示稳定代偿,6例失代偿前1-3月其细胞密度为400—540个/mm~2提示植片将面临失代偿的可能,当细胞密度小于400个/mm~2时,植片透明率为零,本文同时提出促进植片失代偿的有关因素,以供临床参考。 The non-contact corneal endothelium microscope was used to observe the 60-year-old and 60-year-old transplanted endothelium after 6-year and 10-year follow-up. Among 55 eyes, the grafts were transparent with a cell density of 720-1680 cells / mm ~ 2, which showed stable compensation. Six of them showed cell density of 400-540 cells / mm ~ 2 from January to March before decompensation Film will face the possibility of decompensation, when the cell density is less than 400 / mm ~ 2, the transparency of the graft is zero, this paper also put forward to promote the factors related to plant decompensation for clinical reference.