作者报告了用小剂量氢氯噻嗪(50mg/日)和氨氯吡咪(5mg/日)治疗519例复发性肾结石病人5年的经验。其中约50%的病人并用了别嘌呤醇(100mg/日)作辅助治疗。全部病人均有活动性结石形成,有65%的病人伴有高尿钙症,24%伴有高尿酸症。给予小剂量氢氯噻嗪,大多数病人尿 The authors report on 5 years of experience in treating 519 patients with recurrent nephrolithiasis with small doses of hydrochlorothiazide (50 mg / day) and amiloride (5 mg / day). Approximately 50% of patients and allopurinol (100mg / day) for adjuvant therapy. All patients had active calculus, with 65% of patients with hypercalciuria and 24% of patients with hyperuricemia. Given a small dose of hydrochlorothiazide, most patients urine