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胆管癌早期诊断困难 ,手术切除率低。姑息性治疗的平均生存期为 1年 ,但 5年生存率仍较低。目前 ,对胆管癌的生物学行为和预后影响因素的了解还不深入。转化生长因子 (ＴＧＦ) β1和转化生长因子 β受体Ⅱ (ＴβＲⅡ )是生长因子家族的成员 ,ＴＧＦ β1与细胞膜上的ＴＧＦ β1
Early diagnosis of cholangiocarcinoma is difficult and the resection rate is low. The average survival of palliative care is 1 year, but the 5-year survival rate is still low. At present, the understanding of the biological behaviors and prognostic factors of cholangiocarcinoma is not yet in depth. Transforming growth factor (TGF) β1 and transforming growth factor β receptor II (TβRII) are members of the growth factor family, TGF β1 and TGF β1 on the cell membrane