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肿瘤浸润性淋巴细胞(TIL)介导的免疫反应在机体抗肿瘤机制中起着重要作用,而细胞因子能够高效调节TIL的生物活性。本文主要综述了膀胱癌TIL免疫生物学特性、IL-2联合IL-4对TIL的免疫调节效应以及TIL体内应用方面的研究进展
Tumor-infiltrating lymphocytes (TIL) -mediated immune response plays an important role in the anti-tumor mechanism of the body, and cytokines can effectively regulate the biological activity of TIL. This review summarizes the immunobiological properties of TIL in bladder cancer, the immunomodulatory effects of IL-2 and IL-4 on TIL, and the progress in the application of TIL in vivo