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目的观察酚妥拉明对慢性肺源性心脏病心衰患者的疗效,为临床治疗提供依据。方法将70例患者随机分为治疗组和对照组各35例。两组采用常规内科治疗如控制感染、氧疗、强心、利尿等,治疗组在上述治疗基础上加用酚妥拉明10mg加入生理盐水50ml中微泵静脉推注(5ml/h),1次/d,疗程均为10d。结果治疗组的疗效、临床症状、血气分析及心功能的改善优于对照组,差异具有统计学意义(P<0.05)。结论酚妥拉明对慢性肺源性心脏病心衰患者具有良好的疗效及安全性,值得临床推广应用。
Objective To observe the curative effect of phentolamine on patients with heart failure due to chronic cor pulmonale and provide basis for clinical treatment. Methods 70 patients were randomly divided into treatment group and control group of 35 cases. The two groups were treated with conventional medical treatment such as infection control, oxygen therapy, cardiac, diuretic, etc. The treatment group was treated with intravenous injection of phentolamine 10mg (50ml / h) Times / d, treatment are 10d. Results The curative effect, clinical symptoms, blood gas analysis and cardiac function improvement in the treatment group were better than those in the control group, with statistical significance (P <0.05). Conclusion Phentolamine has a good curative effect and safety for patients with heart failure of chronic cor pulmonale, which is worthy of clinical application.