论文部分内容阅读
经皮肤肾活检证实的ＩｇＡ肾病４９例，分析其免疫荧光、电镜所见与临床表现及肾功能之间的关系，发现临床表现为镜下血尿、肾病综合征，或伴有高血压及肾功能损害者，其病理变化多较严重。在免疫荧光检查中，多数同时存在有ＩｇＡ、ＩｇＧ及ＩｇＭ沉积。电镜检查示电子致密物广泛沉积在系膜内、内膜下及上皮下，或者同时存在于系膜区和基底膜内，多提示预后不良。
In 49 cases of IgA nephropathy confirmed by skin biopsy, the relationship between immunofluorescence, electron microscopy and clinical manifestations and renal function was analyzed. The clinical manifestations were microscopic hematuria, nephrotic syndrome, or hypertension and renal function Damage, the pathological changes are more serious. In immunofluorescence, most of the simultaneous presence of IgA, IgG and IgM deposition. Electron microscopy showed that electron dense matter was widely deposited in mesangial, subendothelial and subepithelial, or in both mesangial and basilar membrane, suggesting that the prognosis was poor.