曲尼司特是一种过敏介质阻释剂 ,70年代由日本学者Ｋｏｄａ等研制成功[1 ] ,并于1982年上市。国内 1984开始研制 ,1988年获得生产批文。最初 ,主要用于Ｉ型变态反应性疾病如支气管哮喘和过敏性鼻炎的治疗 ,后来发现该药亦有抗ＩＩ型、ＩＩＩ型、ＩＶ型变态反应等多种作用 ,其适 Tranilast is an allergic mediator, which was successfully developed by Japanese scholar Koda in the 1970s [1] and was released in 1982. Domestic 1984 began to develop, 1988 production approval. Initially, mainly for type I allergic diseases such as bronchial asthma and allergic rhinitis treatment, and later found that the drug also has anti-type II, type III, type IV allergy and other effects, its fitness