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目的对比观察胸腔镜与开胸肺叶切除术治疗早期非小细胞肺癌(NSCLC)的临床疗效。方法 90例早期非小细胞肺癌患者,随机分为A组和B组,各45例。A组患者给予开胸肺叶切除术进行治疗,B组患者给予胸腔镜进行治疗,比较两组临床疗效。结果 A组手术时间为(150.24±37.61)min,术中出血量为(153.22±43.55)ml,术后引流时间为(4.58±0.73)d,淋巴结清扫个数为(30.24±0.84)个,视觉模拟评分法(VAS)评分为(6.88±1.20)分;B组分别为(145.36±35.73)min、(75.23±23.94)ml、(2.32±0.34)d、(29.43±0.92)个、(4.33±0.77)分。除手术时间、清扫淋巴结个数比较差异无统计学意义(P>0.05)外,B组其他观察指标均优于A组(P<0.05)。结论胸腔镜手术治疗早期非小细胞肺癌疗效确切,恢复时间短,安全性高,值得临床使用和积极推广。
Objective To compare the clinical effects of thoracoscope and open lobectomy in the treatment of early non-small cell lung cancer (NSCLC). Methods Ninety patients with early stage non-small cell lung cancer were randomly divided into group A and group B, with 45 cases in each group. Patients in group A were treated by open lobectomy, patients in group B were treated by thoracoscope, and the clinical efficacy was compared between the two groups. Results The operation time of group A was (150.24 ± 37.61) min, the amount of bleeding during operation was (153.22 ± 43.55) ml, the time of drainage after operation was (4.58 ± 0.73) d, the number of lymph node dissection was (30.24 ± 0.84) The score of VAS was (6.88 ± 1.20) points in group B, and (145.36 ± 35.73) min in group B (75.23 ± 23.94) ml and (2.32 ± 0.34) d respectively, (29.43 ± 0.92) and 0.77) points. Except for the operation time and the number of lymph nodes dissected there was no significant difference (P> 0.05), other indexes in group B were better than those in group A (P <0.05). Conclusion Video-assisted thoracoscopic surgery for early non-small cell lung cancer has definite curative effect, short recovery time and high safety. It is worth clinical application and promotion.