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以廉价的卤化钾为卤源,Oxone为氧化剂,一系列烯丙胺在温和的条件下经过卤环化反应以较好的产率得到5-卤甲基-2-噁唑啉.该方法的优势在于应用了便宜的卤源,没有有机副产物的产生,具有成本低廉和环保友好的特点.5-卤甲基-2-噁唑啉还可以通过不同的亲核取代反应得到许多有用的衍生物.“,”With inexpensive potassium halide (KX) as halogen source,and oxone as oxidant,a series of allylamides under-went halocyclization reaction and generated 5-halomethyl-2-oxazolines in good to excellent isolated yields under mild condi-tions.The protocol showed attractive advanced features including low cost of halogen source,absence of organic byproduct,and resultant environmental-friendly nature.In addition,various useful derivatives could be expected by proper nucleophilic substitution reactions.