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目的:观察扶正抗癌汤与FOLFOX4联合治疗晚期胃癌患者的临床效果。方法:将70例晚期胃癌患者随机分为观察组和对照组各35例,对照组行FOLFOX4治疗,观察组行扶正抗癌汤与FOLFOX4联合治疗,观察两组患者临床效果。结果:治疗后,观察组临床症状评分(2.20±0.65)分显著优于对照组的(9.45±1.32)分,毒副反应的分度较对照组轻,且KPS评分总有效率(71.43%)显著高于对照组(34.29%),差异均具有统计学意义(P均<0.05)。结论:采用扶正抗癌汤联合FOLFOX4治疗晚期胃癌效果显著,安全性高,值得临床推广应用。
Objective: To observe the clinical effect of Fuzheng Kangai Decoction combined with FOLFOX4 in the treatment of patients with advanced gastric cancer. Methods: Seventy patients with advanced gastric cancer were randomly divided into observation group (35 cases) and control group (35 cases). The control group received FOLFOX4 treatment. The observation group was given Fuzheng Kang Cancer Decoction combined with FOLFOX4 to observe the clinical effect of the two groups. Results: After treatment, the clinical symptom score (2.20 ± 0.65) in the observation group was significantly better than that in the control group (9.45 ± 1.32), the degree of toxicity was lighter than that of the control group, and the total effective rate of KPS was 71.43% Which was significantly higher than that of the control group (34.29%), the differences were statistically significant (all P <0.05). Conclusion: The treatment of advanced gastric cancer with Fuzheng Kang Cancer Decoction combined with FOLFOX4 is effective, safe and worthy of clinical application.