论文部分内容阅读
目的了解大理地区健康人群中麻疹、白喉、甲型肝炎抗体水平及乙型肝炎表面抗体,评价疫苗接种效果和人群免疫状况。方法按照分层和随机的方法抽取样本,采用酶联免疫吸附试验(ELISA)检测,按照县市、年龄、性别进行分组并采用卡方检验,比较组间差异。结果在性别组间麻疹、白喉、甲型肝炎的Ig G及乙型肝炎表面抗体差异均无统计学意义(P>0.05);在年龄组间麻疹Ig G、乙型肝炎表面抗体差异均无统计学意义(P>0.05),白喉、甲型肝炎的Ig G差异均有统计学意义(P<0.05);在县市组间麻疹、白喉、甲型肝炎的Ig G差异均有统计学意义(P<0.05),乙型肝炎表面抗体差异无统计学意义(P>0.05)。结论应提高麻疹、白喉、甲型肝炎、乙型肝炎疫苗的常规接种率,加强>6岁的人群白喉及学龄前儿童甲型肝炎的预防接种。
Objective To understand the levels of measles, diphtheria and hepatitis A (HBsAg) and hepatitis B surface antigen (HBsAg) in healthy population in Dali, and to evaluate the vaccination effect and population immune status. Methods The samples were stratified and randomized. The samples were detected by enzyme-linked immunosorbent assay (ELISA), grouped by county, age and sex, and analyzed by chi-square test. The differences among groups were compared. Results There was no significant difference in Ig G and HBsAg between measles, diphtheria and hepatitis A among the sex groups (P> 0.05). There was no statistical difference in Ig G and HBsAg among the age groups (P> 0.05) .IgG of diphtheria and Hepatitis A had statistical significance (P <0.05). IgG of measles, diphtheria and Hepatitis A were significantly different between counties and cities (P> 0.05) P <0.05), there was no significant difference in HBsAg (P> 0.05). Conclusions The conventional immunization rates of measles, diphtheria, hepatitis A and hepatitis B should be increased, and hepatitis A vaccination of diphtheria and preschool children> 6 years old should be strengthened.