论文部分内容阅读
作者对83例多发性硬化(PC)患者血浆与其中40例脑脊液的循环单磷酸腺甙和循环单磷酸鸟苷浓度,以及其比值进行了研究。女49例,男34例。多数患者年龄为20～40岁。其中查血浆脑脊髓型73例(35例),脊髓型8例(5例)和脑型2例。病情呈重度者查血浆5例(4例),中度69例(36例)和轻度9例。疾病呈缓解过程者查血浆73例(32例),进行性者9例(8例)和初次发病者1例。病程在2年以内者查血浆23例(14例),2～5年者33例(18例)和5年以上者27例(8例)。并用20人同龄健康者血浆和14例有周围神经系统损害、脑蛛网膜炎与脑炎后遗症患者的循环核苷酸作对照。研究结果如下:
The authors studied the concentrations of circulating monophosphate and cyclic monophosphate monophosphate in 83 patients with multiple sclerosis (PC) plasma and in 40 of them with cerebrospinal fluid and their ratios. 49 women, 34 males. Most patients are 20 to 40 years of age. Among them, 73 cases (35 cases) were diagnosed as cerebral spinal cord type, 8 cases (5 cases) of spinal cord type and 2 cases of brain type. Severe cases were investigated in 5 cases of plasma (4 cases), moderate in 69 cases (36 cases) and mild in 9 cases. The disease was alleviated in 73 cases of plasma (32 cases), progressive in 9 cases (8 cases) and primary onset in 1 case. The course of disease in less than 2 years to check the plasma in 23 cases (14 cases), 2 to 5 years in 33 cases (18 cases) and more than 5 years in 27 cases (8 cases). 20 healthy subjects with plasma and 14 cases of peripheral nervous system damage, cerebral arachnoiditis and encephalitis sequelae of patients with circulating nucleotides as a control. The results are as follows: