论文部分内容阅读
本文报道主链含5-氟脲嘧啶聚酯的合成及抗动物肿瘤初步试验。将5-氟脲嘧啶在二甲基甲酰胺中与无水碳酸钾作用,所生成的5-氟脲嘧啶钾盐随即与双氯乙酸二醇酯进行共缩聚,得到了6种主链含5-氟脲嘧啶的聚酯。同时还合成了三种新的双氯代乙酸二醇酯单体。
This article reports the synthesis of 5-fluorouracil-containing polyesters in the main chain and preliminary studies on animal tumors. 5-Fluorouracil was reacted with anhydrous potassium carbonate in dimethylformamide. The resulting 5-fluorouracil potassium salt was copolycondensated with di-chloroacetic acid diol to obtain six main chain containing 5 - Fluorouracil polyesters. Three new dichloroacetate monomers were also synthesized.