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目的:探讨连续性肾脏替代治疗(CRRT)在II型心肾综合征中的临床疗效。方法:收集行连续性肾脏替代治疗(CRRT)的II型心肾综合征患者20例,分别测定并比较每例连续性肾脏替代治疗(CRRT)患者治疗前和治疗后平均动脉压(MAP)、氧合指数(PaO_2/FiO_2)、血浆氨基末端B型利钠肽前体(NT-pro BNP)、血肌酐(Cr)、尿素氮(BUN)及血清C-反应蛋白(CRP)指标的变化情况。结果:连续性肾脏替代治疗(CRRT)治疗前后MAP、CRP差异无统计学意义(P>0.05),而PaO_2/FiO_2、NT-proBNP、BUN及Cr均较治疗前明显好转,差异有统计学意义(P<0.05)。结论:连续性肾脏替代治疗(CRRT)应用于Ⅱ型心肾综合征患者,临床效果满意,无明显不良反应。
Objective: To investigate the clinical effect of continuous renal replacement therapy (CRRT) in type Ⅱ cardio-renal syndrome. Methods: Twenty patients with type II cardio-renal syndrome who underwent continuous renal replacement therapy (CRRT) were enrolled in this study. Mean arterial pressure (MAP), pre-treatment and post-treatment mean arterial pressure (MAP) PaO 2 / FiO 2, NT-pro BNP, Cr, BUN and CRP . Results: There was no significant difference in MAP and CRP between before and after treatment of continuous renal replacement therapy (CRRT) (P> 0.05), while PaO_2 / FiO_2, NT-proBNP, BUN and Cr were significantly improved (P <0.05). CONCLUSIONS: Continuous renal replacement therapy (CRRT) is used in patients with type Ⅱ heart-kidney syndrome. The clinical effect is satisfactory with no obvious adverse reactions.