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目的分析了2型糖尿病(DM2)患者血浆GHbA1C水平与Hcy水平的相关性。方法应用直接酶法和两点速率法分别对61例2型糖尿病患者血浆GHbA1C水平与Hcy水平进行测定,并与35例正常健康者作比较。结果 2型糖尿病患者血浆GHbA1C水平与Hcy水平非常显著地高于正常对照组(P<0.01),血浆GHbA1C水平与Hcy水平呈显著正相关(P<0.01)。结论检测2型糖尿病患者血浆GHbA1C水平与Hcy水平的变化对疗效观察、预后判断均具有重要的临床价值。
Objective To analyze the correlation between plasma GHbA1C level and Hcy level in type 2 diabetes mellitus (DM2). Methods The levels of GHbA1C and Hcy in 61 patients with type 2 diabetes mellitus were measured by direct enzymatic method and two-point rate method, respectively, and compared with 35 normal controls. Results The levels of plasma GHbA1C and Hcy in type 2 diabetic patients were significantly higher than those in normal controls (P <0.01). There was a significant positive correlation between plasma GHbA1C levels and Hcy levels (P <0.01). Conclusion The changes of plasma GHbA1C level and Hcy level in type 2 diabetic patients have important clinical value in the observation of curative effect and prognosis.