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白细胞端粒长度(leucocyte telomere length,LTL)是衰老的生物标志物,较短的LTL与不良的心血管预后相关。端粒再生能力降低可能是其机制之一。骨髓来源的循环祖细胞(progenitor cells,PCs)参与组织修复和再生。该研究的目的是研究LTL与PCs之间的关系及其对不良心血管预后的影响。方法:通过定量聚合酶链反应测定566例冠状动脉疾病
Leukocyte telomere length (LTL) is a biomarker of aging and shorter LTL is associated with poor cardiovascular outcomes. Decreased telomere regeneration may be one of its mechanisms. Bone marrow-derived progenitor cells (PCs) are involved in tissue repair and regeneration. The purpose of this study was to investigate the relationship between LTL and PCs and their effect on adverse cardiovascular outcomes. Methods: 566 cases of coronary artery disease were determined by quantitative polymerase chain reaction